Listen to media call. FDA Expands Eligibility for COVID-19 Vaccine Boosters. This military report finally shed light on LTCs crumbling house of cards. COVID-19; COVID-19 vaccine; plastic surgery; scar formation; vaccination; vaccine hesitancy; wound healing. The U.S. Food and Drug Administrations Center for Biologics Evaluation and Research (CBER) will convene a virtual meeting of the Vaccines and Related Biological Products Advisory Committee (VRBPAC) on June 10, 2021, via webcast. Management of the wound care clinic during the novel coronavirus pneumonia pandemic period: Sharing of management experience in a general hospital of China. So, every time someone comes to me and says they cant do it anymore, I ask, Have you gotten your vaccine? Its like being in the middle of the ocean and thats our lifeline. Karmisholt KE, Banzhaf CA, Glud M, Yeung K, Paasch U, Nast A, Haedersdal M. Br J Dermatol. Scar formation was evaluated according to the Patient and Observer Scar Assessment Scale (POSAS) after a 3-month follow-up. Today, the FDA added new devices to the device discontinuance list, including sterilization products and oxygen conservers. In December of 2019 the World Health Organization (WHO) was informed of an unknown virus causing pneumonia like symptoms in Wuhan City, Hubei Province of China. The FDA has scheduled a meeting of its Vaccines and Related Biological Products Advisory Committee; alerted health care professionals and compounders of potential risks associated with compounding remdesivir drug products; revised the Letter of Authorization for COVID-19 convalescent plasma; and issued a statement that FDA continues important work to support medical product development to address new virus variants. Lazarus JV, Ratzan SC, Palayew A, Gostin LO, Larson HJ, Rabin K, et al. One surgeon performed the surgeries, which avoided the bias of different surgical techniques. Coronavirus (COVID-19) Update: FDA Actively Working to Investigate, Address Potential Impacts of Omicron Variant; Urges Vaccination and Boosters. However, global surveys have revealed that ~30% of participants were hesitant about COVID-19 vaccination (2, 3). FDA Leadership to Accelerate the Recovery from COVID-19, Remarks by Deputy Commissioner for Medical and Scientific Affairs Anand Shah, M.D. Llame al 1-833-364-0425. Doctors also lack adequate evidence to address vaccine hesitancy, and many doctors are vaccine-hesitant themselves (4, 5). Wann du [Deitsch (Pennsylvania German / Dutch)] schwetzscht, kannscht du mitaus Koschte ebber gricke, ass dihr helft mit die englisch Schprooch. FDA announced that a public meeting of the Vaccines and Related Biological Products Advisory Committee will be held on Oct. 22, 2020. Hospital News Canada, Digital healthcare start-ups building solutions for aging adults to watch for 2021, Triage in critical care: A protocol to protect lives and principles, Creating the Sharing Circle website : Providing culturally safe information to support wound, ostomy and continence care in Indigenous communities, Brainstorming ways to bring wound care directly to those in need, Harm reduction dispensing machines to be installed across Canada, Saving organs, saving lives: Building the worlds first organ regeneration lab, AI-powered tool on surgical unit to improve patient care, Sexual assault survivors face significant barriers to care, Local cancer free after successful surgery - Energeticcity.ca, Ontario Nurses' Association says bargaining with, Major union joins community effort to save Lachine. POSAS observer scale at three-month follow-up; vaccination interval was defined as an interval between the time of the last dose of COVID-19 vaccination and the time of surgical sutures. The aim of this study was to compare the wound healing effects of binuclear dinitrosyl iron complexes with glutathione (B-DNIC-GSH) and NO-containing gas flow (NO-CGF) at their optimal NO . COVID-19 is highly contagious and its rapid spread burdens the healthcare system. A CTV News article published in 2020, Man rotting alive from bedsore dies of infection, revealed the high incidence of pressure injuries in long term care (LTC) residents. Aesthetic outcome of simple cuticular suture distance from the wound edge on the closure of linear wounds on the head and neck: A randomized evaluator blinded split-wound comparative effect trial. Federal government websites often end in .gov or .mil. Hesitancy is primarily driven by vaccine safety concerns (6). BritneyAnn Butt, MClSc-WH, BScN, RN, NSWOC, WOCC(C) is the Wound Ostomy Continence Institute Program Development Coordinator / Skin Wellness Associate Nurse Program Lead/ NSWOC Core Program Lead SWAN Community of Practice The Wound, Ostomy & Continence Institute. Im also proud of all of our caregivers, but now we need to do whats right for ourselves and for society to get rid of this pandemic. FOIA JAMA. There is a clear and critical need for nurses specialized in wound, ostomy, and continence care (NSWOC) which can integrate evidence-based best practises into their care setting, provide ongoing education to staff, and assess and provide recommendations on wound, WOC related issues. Health care providers specialized in WOC care are required if we want to have a significant improvement in the health outcomes of our patients. The public may be concerned that COVID-19 vaccination will cause side effects similar to viral infections mentioned above to affect wound healing and even lead to hypertrophic scar formation. Wrafter PF, Murphy D, Nolan P, Shelley O. National Library of Medicine Its well known that the coronavirus has inflicted immeasurable hurt on the elderly. Perhaps symbolically, this impact has included the area of wound care, whose practices themselves have been touched negatively by the pandemic. Learn more about COVID-19 vaccine safety monitoring from FDA Commissioner Dr. Stephen Hahn. Ruf selli Nummer uff: Call 1-844-372-8349. FDA, CDC, and NIH are engaged in a science-based, rigorous process to consider whether or when a booster might be necessary. 10.1101/2021.02.03.21251054 Expiration of California, federal COVID emergencies could end some free 1. return to JAMA's Q&A series to discuss the Pfizer/BioNTech and Moderna vaccines: the data, the weekend's EUA designation (Pfizer/BioNTech), and the process for future full licensure and postmarketing safety surveillance. No complications were observed in any patients. However, cases like these are being exposed and reported in the media. The main outcomes were the scale scores of wound healing and scar formation. Other myths theyve heard include things like the vaccine actually gives you a mild case of COVID-19, if youve had COVID-19 you dont need to get this vaccine, the vaccine can alter your DNA, the vaccine contains fetal tissue, and the vaccine contains a microchip that the government will use to track people. ET. Third, because the patients in this study came from a single center and were treated by a single surgeon, the conclusions may not be applicable to patients in other centers and treated by other surgeons. With the incorporation of the skin wellness associate nurses (SWAN) as a member of the WOC team, LTC facilities can have access to on-site WOC care, providing rapid assessment, bedside WOC support to staff and wisely utilize health care spending. This study has some limitations. National Library of Medicine Each item of POSAS observer scale. It is created by eHealthMe based on reports of 15 people who have Wound infection from the Food and Drug Administration (FDA), and is updated regularly. 2022 May;38(4):e3520. Does wound eversion improve cosmetic outcome? OBAVJETENJE: Ako govorite srpsko-hrvatski, usluge jezike pomoi dostupne su vam besplatno. and Director, FDA Center for Biologics Evaluation and Research, Peter Marks, M.D., Ph.D., discuss the Pfizer-BioNTech COVID-19 Vaccine booster dose. Nature. In the spring of 2020, the Canadian military was deployed to several Ontario LTC facilities that were identified as needing staffing support and relief. Find out more about herd immunity, Operation Warp Speed, and vaccine distribution in this episode. Epub 2021 Oct 29. Located in the Prineville hospital, the clinic is open Monday through Friday, 8 a.m.-5 p.m. by appointment only. Who is accountable for this? Moreover, cutaneous small-vessel vasculitis after COVID-19 vaccination has also been reported, which may aggravate these existing cutaneous injuries (23, 24). The CDC says the vaccines. Today, FDA announced that it has found certain lots of Astra Zeneca COVID-19 vaccine drug substance manufactured at the Emergent facility in Baltimore, Maryland, to be acceptable for use for potential export. doi: 10.1093/asj/sjz017, 20. The AstraZeneca vaccine is not authorized for use in the U.S., but FDA understands that these AstraZeneca lots, or vaccine made from the lots, will now be exported for use. Update: The FDA updated this safety communication to clarify that the ACON Flowflex SARS-CoV-2 Antigen Rapid Test (Self-Testing) in dark blue packaging is a product of ACON Biotech (Hangzhou) Co., Ltd. FDA Postpones Advisory Committee Meeting to Discuss Request for Authorization of Pfizer-BioNTech COVID-19 Vaccine for Children 6 Months Through 4 Years of Age. Prevalence and correlates of vaccine hesitancy among general practitioners: a cross-sectional telephone survey in France, April to July 2014. The https:// ensures that you are connecting to the Sallam M. COVID-19 vaccine hesitancy worldwide: a concise systematic review of vaccine acceptance rates. The InspectIR COVID-19 Breathalyzer test is the first COVID-19 diagnostic test that detects chemical compounds in breath samples associated with SARS-CoV-2 infection. SARS-Coronavirus-2 cases in healthcare workers may not regularly originate from patient care: lessons from a university hospital on the underestimated risk of healthcare worker to healthcare worker transmission. Careers. doi: 10.1371/journal.pone.0244126, 16. The physicians in your community are your experts, commented Dr. John Mohart. doi: 10.1016/j.puhe.2021.02.025, 22. (A) painful; (B) itching; (C) color; (D) stiff; (E) thickness; (F) irregular. Laser treatments in early wound healing improve scar appearance: a randomized split-wound trial with nonablative fractional laser exposures vs. untreated controls. Learn More About COVID-19 Vaccines From the FDA. immune thrombotic thrombocytopenia, autoimmune liver diseases, Guillain-Barr syndrome, IgA nephropathy, rheumatoid arthritis and systemic lupus erythematosus). A total of thirty-one patients were included in the final cohort. The vaccination interval was defined as the interval between the last dose of the COVID-19 vaccine and when surgical sutures were introduced. Clipboard, Search History, and several other advanced features are temporarily unavailable. J Am Acad Dermatol. Patients such as Lilly deserve better. Coronavirus (COVID-19) Update: FDA Announces Advisory Committee Meeting to Discuss Janssen Biotech Inc.s COVID-19 Vaccine Candidate. Joint COVAX Statement on Supply Forecast for 2021 and early 2022 Hoffmann explained that wound care among the elderly has suffered during the pandemic when routine medical visits, including many to wound clinics, were drastically reduced because this care was considered nonessential.. According to data available at press time, while COVID-19 cases in all long-term care facilities accounted for 8% of total cases nationwide, they accounted for 41% of all COVID-19-related deaths, the American Health Care Association reported in October. XM: concept of the study, designing experiments, and writing and editing the manuscript. CHICAGO, April 13, 2020 /PRNewswire/ -- The patients most vulnerable to contract the coronavirus, are the same group that suffer from chronic, non-healing wounds. Hospital News is published monthly and is made available in distribution racks placed in high traffic areas in hospitals and related institutions across the country. Would you like email updates of new search results? View livestream, Coronavirus (COVID-19) Update: FDA Allows More Flexible Storage, Transportation Conditions for Pfizer-BioNTech COVID-19 Vaccine. Results: This is likely due to a short period, during which cutaneous reactions caused by COVID-19 vaccination occur. government site. The FDA published new information about the vaccine development and review process: FDA and VaccinateYour Family Talk COVID With Minority Community Leaders. Dr. Ann-Elizabeth further elaborated on the concerns of people of color getting the vaccine, saying, Historically, trials were mostly done on white men, but things have changed. CD: conducting the surgeries, designing the study, acquiring data, and writing the manuscript. In this study, patients with adult trauma with subcutaneous sutures placed by a single plastic surgeon in a single center were included. Copyright 2022 Dong, Yu, Quan, Wei, Wang and Ma. Between one and 3.5 million incontinence cases, almost 10 per cent of the Canadian population, have been reported. The FDA has advised manufacturers seeking to update their COVID-19 vaccines that they should develop modified vaccines that add an omicron BA.4/5 spike protein component to the current vaccine composition to create a two component (bivalent) booster vaccine, beginning in Fall 2022. To achieve population immunity, a large majority of people has to participate. FDA In Brief: FDA to Hold Advisory Committee Meeting to Discuss Pfizer-BioNTechs Application for COVID-19 Booster. Verger P, Collange F, Fressard L, Bocquier A, Gautier A, Pulcini C, et al. doi: 10.1007/s00403-021-02190-6, 30. Coronavirus (COVID-19) Update: FDA Makes Two Revisions to Moderna COVID-19 Vaccine Emergency Use Authorization to Help Increase the Number of Vaccine Doses Available. Sperm parameters before and after COVID-19 mRNA vaccination. Justus-Liebig University Giessen Department of Oral and Maxillofacial Surgery, Germany, University of Arkansas for Medical Sciences, United States, Panimalar Medical College Hospital and Research Institute, India. Differences in continuous data and ranked data were evaluated by the KruskalWallis test, and categorical data were evaluated by Fisher's exact test. Wound infection and Stress and anxiety - eHealthMe Disclaimer. doi: 10.1111/jocd.14452, 25. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The study appears in Nature Medicine. (2021) 194:24551. I'm the FDA point person on COVID-19 vaccines. Coronavirus (COVID-19) Update: FDA Advisory Committee Meeting to Discuss Request for Authorization of Pfizer-BioNTech COVID-19 Vaccine for Children 6 Months Through 4 Years of Age. Prevalence and correlates of vaccine hesitancy among general practitioners: a cross-sectional telephone survey in France, April to July 2014. 2020 Nov;2(4):100180. doi: 10.1016/j.ajogmf.2020.100180. First, the follow-up to determine scar formation ended at 3 months because of the widespread prevalence of booster doses on the Chinese mainland. and transmitted securely. Chow S, Shao J, Wang H. Sample Size Calculations in Clinical Research. Surgical Infection Society Guidance for Operative and Peri-Operative Care of Adult Patients Infected by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). If patients were vaccinated both pre- and post-operatively, the researchers would not have known exactly which dose affected the patients. We believe that the risks of COVID infection far outweigh the risks of receiving the vaccine. doi: 10.1016/j.det.2021.05.016, 23. Before Research on wound healing and scar formation is highly valued by plastic surgeons (11, 12). FDA authorized undiluted, thawed Pfizer-BioNTech COVID-19 Vaccine vials to be stored in the refrigerator at 2C to 8C (35F to 46F) for up to 1 month. How do we prevent this? Do they take the risk of exposing their patients to the virus, or do they continue with the much-needed wound care?, From the November 2020 Issue of McKnight's Long-Term Care News. -, Ward JK, Colgrove J, Verger P. France's risky vaccine mandates. Today, the FDA announced that it is allowing undiluted frozen vials of the Pfizer-BioNTech COVID-19 Vaccine to be transported and stored at conventional temperatures commonly found in pharmaceutical freezers for a period of up to two weeks. Timing of COVID-19 vaccination in the major burns patient. New-onset autoimmune phenomena post-COVID-19 vaccination J Appl Physiol. An Update from Federal Officials on Efforts to Combat COVID-19. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The Vaccines and Related Biological Products Advisory Committee will meet in open session to discuss the matter of additional doses of COVID-19 vaccines and specifically to discuss the Pfizer-BioNTech supplemental Biologics License Application for administration of a third (booster) dose of Comirnaty (COVID-19 Vaccine, mRNA) in individuals 16 years of age and older. The FDA posts translations of the Moderna COVID-19 Vaccine fact sheet in multiple languages, issues new ANDAs, and provides a testing update. All authors contributed to the article and approved the submitted version. Boca Raton: Chapman & Hall/CRC Biostatistics Series (2008). Vaccine Ready: Addressing COVID-19 Health Disparities among Racial and Ethnic Minority Communities. The .gov means its official. The site is secure. Troiano G, Nardi A. , 1-844-802-39271-844-372-8337. COVID-19 Vaccines: Myth Versus Fact | Johns Hopkins Medicine 2018 Dec;179(6):1307-1314. doi: 10.1111/bjd.17076. COVID-19 Vaccine Market Analysis| Market Report 2021 FDAs Office of Minority Health and Health Equity discusses the agencys efforts to stop fraudulent products from reaching our markets, especially those claiming to prevent, treat, or cure COVID-19. Coronavirus (COVID-19) Update: FDA Shortens Interval for Booster Dose of Moderna COVID-19 Vaccine to Five Months. FDA Limits Use of Janssen COVID-19 Vaccine to Certain Individuals. Subgroup analyses were conducted to evaluate the effects of different COVID-19 vaccine types. The risk of getting COVID is very real and very dangerous. Pregnant women are at an increased risk for COVID complications. PMC (2022) 21:1936. Figure 2. Collier DA, Ferreira I, Kotagiri P, Datir RP, Lim EY, Touizer E, et al. Largest study of COVID-19 vaccine skin reactions shows a wide range of FDA Expands Eligibility for Pfizer-BioNTech COVID-19 Vaccine Booster Dose to Children 5 through 11 Years. An FDA staff memberdiscusses how her former hesitancy and fear grew into hope and a willingness to receive a COVID-19 vaccine. Before sharing sensitive information, make sure you're on a federal government site. However, in vaccine type, the proportions of inactivated vaccine in the three groups were 62.5, 100, and 54.5%, respectively (p =.027). FDA to Hold Meeting of its Vaccines and Related Biological Products Advisory Committee to Discuss Pediatric Use of COVID-19 Vaccines. We'll make sure they're safe and effective. ZY: concept of the study, designing the study, acquiring data, and writing the manuscript. J Am Acad Dermatol. The virus, that would ultimately be known as COVID 19 was declared a pandemic by the WHO on March 11th, 2020. No use, distribution or reproduction is permitted which does not comply with these terms. Details of patients' characteristics were shown in Table 1. Global OTC Farmacia. recommended that patients with burn injuries should be vaccinated against SARS-CoV-2 once they recovered from the acute phase of injury (25). This disease has deprived us of human connection and most people would say they would do anything to get their life back. And Im proud of our country for knocking out this vaccine in an astonishing timeframe. to the Alliance for Health Policy, Ensuring The Safety And Effectiveness Of A COVID-19 Vaccine. Comparison of total score of wound assessment inventory (WAI) and patient and observer scar assessment scale (POSAS) between patients undergoing the surgical suture with different vaccination intervals. (A) edema; (B) erythema; (C) exudates. Beneficial Effects of Dinitrosyl Iron Complexes on Wound Healing The sample size was estimated using the following formula (18): According to the previous publication and clinical observations, the average scores on the POSAS patient scale in groups of <1, 1 and <3, and 3 months were estimated to be 30, 28, and 20, respectively (19). Today, the U.S. Food and Drug Administration has limited the authorized use of the Janssen COVID-19 Vaccine to individuals 18 years of age and older for whom other authorized or approved COVID-19 vaccines are not accessible or clinically appropriate, and to individuals 18 years of age and older who elect to receive the Janssen COVID-19 Vaccine because they would otherwise not receive a COVID-19 vaccine. Fourth, this is a descriptive study, some basic conditions of patients, such as wound type, have considerable heterogeneity. A pungent sweet sickly smell permeates the room, it is a distinct odour they have encountered before, the smell of infection. The authorization was based on the FDAs thorough and transparent evaluation of the data that included input from independent advisory committee experts who overwhelmingly voted in favor of making the vaccine available to children in this age group. HHS Vulnerability Disclosure, Help The FDA has scheduled a meeting of its Vaccines and Related Biological Products Advisory Committee (VRBPAC) on Dec. 10 to discuss the request for emergency use authorization (EUA) of a COVID-19 vaccine from Pfizer, Inc. in partnership with BioNTech Manufacturing GmbH. Front Immunol. An official website of the United States government, : Draaijers LJ, Tempelman FR, Botman YA, Tuinebreijer WE, Middelkoop E, Kreis RW, et al. Keywords: The FDA announces revisions to the vaccine recipient and vaccination provider fact sheets for the Johnson & Johnson (Janssen) COVID-19 Vaccine. Statement by FDA Commissioner Stephen M. Hahn, M.D. According to the non-profit Project Perch, the bird was found . Following careful review and deliberation, the U.S. Food and Drug Administration is taking important steps that will allow a critically needed supply of the Janssen (Johnson & Johnson) COVID-19 Vaccine to be made available. COVID-19 vaccines produce an antibody reaction that protects you from the disease. Mohamed L, Madsen A, Schaltz-Buchholzer F, Ostenfeld A, Netea MG, Benn CS, et al. Joint CDC and FDA Statement on Vaccine Boosters. A conversation with Center for Biologics Evaluation and Research director Peter Marks, M.D., Ph.D. FDA In Brief: FDA Issues Guidance on Emergency Use Authorization for COVID-19 Vaccines. If vaccination causes shedding, it typically results . COVID-19 vaccines help our bodies develop immunity to the virus that causes COVID-19 without us having to get the illness. Wound care during the COVID-19 pandemic: improving outcomes through the integration of telemedicine Authors Alisha Oropallo 1 1 2 , John Lantis 3 4 5 , Alexander Martin 6 , Ammar Al Rubaiay 7 , Na Wang 8 Affiliations 1 Comprehensive Wound Healing Center, Department of Vascular Surgery, Northwell Health, NY, US. government site. Close more info about COVID-19 upsets balance of wound healing and practices, McKnights Women of Distinction Awards and Forum, Providers pepper CMS with schizophrenia questions; agency cautions on MDS changes, Nursing home beds fell pre-pandemic, even as aged population exploded: researchers, Reach of AI, other tech will help SNFs reach seniors looking to avoid nursing homes: expert. Batatinha H, Baker FL, Smith KA, Ziga TM, Pedlar CR, Burgess SC, et al. Clin Exp Dermatol. I know some people are a little nervous that this vaccine came out so quickly, but the reason is simple. Kupferschmidt K. Top Israeli immunologist's views on vaccines trigger furor. The committee will discuss the Emergency Use Authorization (EUA) of the ModernaTX Inc. COVID-19 vaccine and the Janssen Biotech Inc. COVID-19 vaccine for the administration of an additional dose, or booster dose, following completion of the primary series, to individuals 18 years of age and older. (2021) 9:60. doi: 10.1101/2020.12.28.20248950, 4. The hardest part of the pandemic is that its almost the exact same population that is most vulnerable to complications from COVID-19 that is most need of wound care, wrote Brian Wallace, founder and president of Louisville-based NowSourcing, an infographic design agency, in a recent McKnights.com blog. *Correspondence: Zhou Yu, yz20080512@163.com; Xianjie Ma, majing@fmmu.edu.cn, COVID-19 Vaccines Safety Tracking (CoVaST): part I, View all
The wound healing and scar formation assessments by the WAI and POSAS are illustrated in Figure 2. (2021) 9:60. Vaccine hesitancy in the era of COVID-19. COVID-19 Vaccines | FDA - U.S. Food and Drug Administration (A) vascularization; (B) pigmentation; (C) thickness; (D) relief; (E) pliability. doi: 10.1111/ced.13814, Keywords: vaccine hesitancy, COVID-19, wound healing, scar formation, vaccination, COVID-19 vaccine, plastic surgery, Citation: Dong C, Yu Z, Quan X, Wei S, Wang J and Ma X (2022) No Differences in Wound Healing and Scar Formation Were Observed in Patients With Different COVID-19 Vaccination Intervals. The FDA posts an updated letter of authorization, health care provider fact sheet and frequently asked questions regarding the number of Pfizer-BioNTech doses in a vial, updated the Device Shortage List, and provides a testing update. FDA amended the emergency use authorization (EUA) for the Pfizer-BioNTech COVID-19 Vaccine to allow for the use of a single booster dose, to be administered at least six months after completion of the primary series with the Pfizer-BioNTech COVID-19 Vaccine in certain populations. However, no change in wound healing is observed in our study, possibly attributing to the fact that inactivated vaccines are the main vaccine type used in the Chinese mainland, and the immune mechanism of inactivated vaccines is the stimulation of non-pathogenic viral proteins to the immune system; this may minimize the influence of virus to the participants or patients. (2021) 326:2734. (1:13), Espaol KoreanCantoneseMandarinTagalogVietnameseCherokeeNavajo, Typical vaccine development process starting in the lab through post-FDA-approval monitoring, Infographic on the path for vaccines from research to FDA approval, Ongoing FDA monitoring of COVID-19 vaccine safety, Dr. Peter Marks, Director of the FDA's Center for Biologics Evaluation and Research, answers questions about COVID-19 vaccines, FDA Commissioner, Dr. Robert Califf discusses COVID-19 vaccine boosters, RADM Araojo discusses FDAs Emergency Use Authorization process with RADM Denise Hinton, FDAs Chief Scientist, Director of the FDA's Center for Biologics Evaluation and Research discusses how the FDA facilitated COVID-19 vaccine development, How the FDA works to stop fraudulent products from reaching the market, Discussingwhether and how the composition for primary doses of the currently available COVID-19 vaccines should be modified and how and whether the composition and schedule for booster doses should be adjusted moving forward, Discussing whether and how to change the SARS-CoV-2 strain composition of COVID-19 vaccines, Discussing data for Modernas COVID-19 Vaccine for children 6 through 17 years of age, Moderna's COVID-19 Vaccine for children 6 months through 5 years of age, and Pfizer-BioNTech's COVID-19 Vaccine for children 6 months through 4 years of age, Discussing data for a Novavax COVID-19 vaccine for those 18 years of age and older, Discussing, in general, COVID-19 vaccine booster doses and strain selection, Discussing data for Pfizer COVID-19 Vaccine for children 5 - 11, Discussing Moderna COVID-19 Vaccine and Janssen COVID-19 Vaccine booster doses, Discussing a third dose or booster of a COVID-19 vaccine, Discussing pediatric use of COVID-19 vaccines, Discussing third emergency use authorization request for a COVID-19 vaccine, Discussing second emergency use authorization request for a COVID-19 vaccine, Discussing first emergency use authorization request for a COVID-19 vaccine, Discussing, in general, the development, authorization and/or licensure of vaccines to prevent COVID-19.